![]() ![]() First, among the human enteric viruses, HuNoVs are recognized as the leading cause of epidemics and sporadic cases of gastroenteritis in all age groups ( De Graaf et al., 2016). Several factors contribute to these outbreaks. As a consequence, they have been implicated in many gastroenteritis outbreaks, and norovirus (HuNoV) is the agent most frequently detected following oyster consumption ( EFSA, 2012 Yu et al., 2015). Shellfish, being filter feeders, are known to accumulate different types of pathogens of human fecal pollution. Quantifying the decrease in viral infectivity and genome detection in oysters over such a long period may help local authorities to manage production areas implicated in shellfish-borne outbreaks, and thus protect consumers. Infectivity decreased faster than genome copies but infectious viruses were detected for several days. ![]() Using the Tulane virus (TV), a norovirus surrogate that recognizes the same ligand as human norovirus in oyster tissues, the genome and infectious virus decay rates were estimated using inverse linear regression in a Bayesian framework for genome copies. Sensitive molecular methods have been set up for shellfish analysis but without answering the question of infectious virus detection. Accumulated virus decays over a period of days to weeks, possibly rendering contaminated oysters safe again. Oysters, being filter feeders, can accumulate some human pathogens such as norovirus, a highly infectious calicivirus, most common cause of acute gastroenteritis worldwide. 3Laboratoire Sécurisation des Productions en Conchyliculture/Santé, Génétique et Microbiologie des Mollusques, Institut Français de Recherche pour l’Exploitation de la Mer (IFREMER), Bouin, France.2Hubert Department of Global Health, Emory University, Atlanta, GA, United States.1Laboratoire de Microbiologie, Laboratoire Santé, Environnement et Microbiologie-Santé, Génétique et Microbiologie des Mollusques, Institut Français de Recherche pour l’Exploitation de la Mer (IFREMER), Nantes, France.David Polo 1 Julien Schaeffer 1 Peter Teunis 2 Vincent Buchet 3 Françoise S. ![]()
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